Recent Advancements in Alginate Hydrogels: A Comprehensive Review
DOI:
https://doi.org/10.36676/dira.v12.i2.10Keywords:
Alginate Hydrogels, Biopolymer, Biomaterials, Tissue, Drug Delivery, Regenerative Medicine, Scaffold Fabrication, Controlled Release, Biomedical Applications, Rheological Analysis, Morphological Characterization, Mechanical Testing, Bioactivity Assessment, Structural Modifications, Nanocomposite, Stimuli-Responsive, Biocompatibility, Bioink, 3D Bioprinting, Emerging, TrendsAbstract
Alginate hydrogels have gained significant attention in recent years due to their unique properties, including biocompatibility, biodegradability, and ease of gelation. This review paper provides a comprehensive overview of the recent advancements in alginate hydrogels, focusing on their synthesis methods, structural modifications, and applications in various fields such as tissue engineering, drug delivery, and regenerative medicine. The paper discusses novel strategies for enhancing the mechanical properties, bioactivity, and functionality of alginate hydrogels, along with emerging trends and future directions in this rapidly evolving field.
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Pawar, S. N., & Edgar, K. J. (2012). Alginate derivatization: a review of chemistry, properties and applications. Biomaterials, 33(11), 3279-3305. DOI: 10.1016/j.biomaterials.2012.01.007
Lee, K. Y., & Mooney, D. J. (2012). Alginate: Properties and biomedical applications. Progress in polymer science, 37(1), 106-126. DOI: 10.1016/j.progpolymsci.2011.06.003
Chen, Y. C., Su, C. J., & Tseng, C. L. (2015). Hierarchical chitosan-3, 4-dihydroxyphenylalanine-alginate hydrogel as a cell delivery vehicle towards liver regeneration. Acta Biomaterialia, 13, 216-227. DOI: 10.1016/j.actbio.2014.11.015
Duan, B., Hockaday, L. A., Kang, K. H., & Butcher, J. T. (2013). 3D bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels. Journal of Biomedical Materials Research Part A, 101(5), 1255-1264. DOI: 10.1002/jbm.a.34440
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Pawar, S. N., & Edgar, K. J. (2012). Alginate derivatization: a review of chemistry, properties and applications. Biomaterials, 33(11), 3279-3305. DOI: 10.1016/j.biomaterials.2012.01.007
